HIGHT QUANTITY MULBERRY LEAF EXTRACT
2016-12-18 20:52 Views:172
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HIGHT QUANTITY MULBERRY LEAF EXTRACT
1> Also named 1-Deoxynojirimycin (DNJ)
2>.Mulberry leaf Extract powder
3>DNJ assay: 1%,
HIGHT QUANTITYMULBERRY LEAF EXTRACT
| HIGHT QUANTITY MULBERRY LEAF EXTRACT Mainfunctions :1. Treatment of diabetes2. Inhibitor of tumor metastasis3. Antiviral4. Weight loss activities5. Free radical scavenging activities HIGHT QUANTITY MULBERRY LEAF EXTRACT Productname:1-Deoxynojirimycin (DNJ)[]:(2R, 3R, 4R, 5S)-2-Hydroxymethyl-piperidine-3, 4,5-triol;D-5-amino-1, 5-dideoxyglucopyranose;1-DNJ MULBERRY LEAF EXTRACT DNJ Plant Source:Mulberry Leaves MULBERRY LEAF EXTRACT DNJ Chemical name: (2R, 3R, 4R,5S)-2-(Hydroxymethyl)-3, 4, 5-piperidinetriol MULBERRY LEAF EXTRACT DNJ Structural formula: C6H13NO4 MULBERRY LEAF EXTRACT DNJ CAS Reg:19130-96-2 MULBERRY LEAF EXTRACT DNJ Molecular weight: 163.18 MULBERRY LEAF EXTRACT DNJ Specification:DNJ assay 1%, 10%, 20% (HPLC) MULBERRY LEAF EXTRACT DNJ Main pharmacology activities 1.Blood sugar lowering activitiesDNJ is an effective inhibitor of α-glucosidase, it can inhibithyperglycemia by reducing the digestion of carbohydrate and theabsorption of glucose. So DNJ can be used to treat diabetes and itscomplication, obesity and the related functional disorder. 2.Inhibition to virus infectionsIt is reported that DNJ is an effective inhibitor to AIDS(HIV). DNJ has a remarkable resistance to virus, its IC50 is1.2~2.5μg/ml, and the inhibition enhances along with the increaseof DNJ concentration. Steinmann E conformed that HIV can be rapidlykilled after adding DNJ to HIV medium in 2007. 3.Inhibition to tumor metastasisDNJ also play an important role in inhibiting tumormetastasis. TsulomuTsuruoka has studied the possible relationshipbetween tumor metastasis and DNJ by constructing black lung tumormodals in mouse.Function principal maybe is that tumor cellsproduce inadequate carbohydrate chain on cells surface caused byDNJ inhibiting ability to α-glucosidase. |
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