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CAS 56-69-9 5-HTP (5-Hydroxytryptophan) Griffonia simplicifoliaextract natural sedative treat insomina and obesity

Griffonia seed extract (5-HTP), USP/EP/JP

CAS 56-69-9

5-HTP

H-5-Hydroxytryptophan

5-Hydroxytryptophan
Griffonia simplicifolia extract
Griffonia seed extract(5-HTP

EINECS 200-284-8

 

5-HTP(5-Hydroxytryptophan) is a derivative of the amino acid tryptophan.In the human body, tryptophan is converted into 5-HTP, which thencan be transformed into serotonin (a potent neurotransmitter in thebrain). Although 5-HTP is not found at any significant level in anormal diet, tryptophan is found in a wide variety of proteinfoods. The 5-HTP used in dietary supplements is derived from theseeds of an African plant (Griffonia simplicifolia).

Benefits
• Relieves mild to moderate depression
• Relieves insomnia and promotes sleep
• Promotes weight loss by suppressing appetite
• Reduces overall sensation of pain (migraine headaches,fibromyalgia, general muscle pain)

 

Mechanism
5-HTP is typically used to treat mild depression based on thetheory that as a precursor to serotonin, supplements of 5-HTP canincrease serotonin levels and influence mood, sleep patterns andpain control. The amino acid, tryptophan, can also be broken downin the body to yield ribose and/or NAD – both of which have beenassociated with increased energy levels. While these are certainlylogical theories, the scientific evidence supporting them remainsfrom mild to moderate as well.

Safety

5-HTP is safe. The safety concern related to5-HTP supplements is the remote possibility for contamination witha compound linked to a disorder known as eosinophilic myalgiasyndrome (EMS). In 1989, an outbreak of EMS (which results inmuscle pain and weakness, vomiting, headache and in rare cases,death) was linked to contaminated tryptophan supplements (not tothe tryptophan per se, but to a contaminant in the tryptophansupplements). As a result, the FDA banned the sale of alltryptophan supplements (a move that has been widely criticized bypeople on both sides of the supplement debate). In some rare cases,5-HTP supplements have been linked (anecdotally) togastrointestinal distress, muscle pain, lethargy andheadaches.

 

5-HTP,extracted from Griffonia simplicifolia seeds, is one of our mostcompetitive products, with many advantages as listed in thefollowing

• Producedwith pure water only
• High purity: over 99%
• NO solvent - residual free
• Pesticide-free
• Peak-X Free
• Crystal white in appearance
• High solubility in water
• High anti-bacteria, and longer shelf life

 

PRODUCT NAME	5-HTP((5-Hydroxytryptophan)
BATCH NO	090925	BATCH SIZE	200 KGS
MANU DATE	2009, 09, 25	SHELF LIFE	2 years
ANALYSIS	SPECIFICATION	RESULTS	TEST METHODS
Appearance	White to gray white fine powder	Complies	Visual
Odor	Characteristic	Complies	Organoleptic
Specific Optical Rotation	-30.9°~-34.7°	-32.5°	CP2000
Solubility	Slightly soluble in water	Complies	/
Loss on Drying	≤10.0%	6.52%	105°C/3hrs
Residue on Ignition	≤0.5%	0.42%	750°C/5hrs
Extract Solvent	Ethanol	Complies	/
Heavy metals	<10ppm	Complies	CP2000
As	<2ppm	Complies	AAS
Residual Solvents	Eur.Pharm.2000	Complies	GC
Total Plate Count	<1000cfu/g	Negative	CP2000
Yeast & Mold	<100cfu/g	Negative	CP2000
E.Coli	Negative	Complies	CP2000
Salmonella	Negative	Complies	CP2000
Assay( on anhydrous basis)
L-5-HTP	≥98.0%	98.45%	HPLC