The molecular weight range of low molecular weight HA(LMW-HA) isyet to be defined to a uniform standard. It usually ranges from3000 to 1 million. Research shows that HAâ????s various biologicalactivities are molecular weight dependent, some of LMW-HAâ????sbiological activities are not reflected in high molecular weight HAwhich would have the opposite effect.

Low molecular weight HA in the human body has a role inpromoting angiogenesis, also a role of immune activation andpromotion of bone formation. In vitro it can promote proliferationof endothelial cell. At the same time there are research datasuggesting that low molecular weight HA is easier to penetrate intothe dermis in the skin absorption than the high molecular weightHA. It promotes lood circulation, regulates skin metabolism,improves skin nutrition, plays a wrinkle beauty care.

Compared with the high molecular weight HA, LMW-HA may showdifferent biological functions. It can stimulate angiogenesis andinduce the expression of inflammatory mediators, inhibit theproliferation of tumor, has the antibacterial effect and so on.Therefore, how to prepare LMW-HA has become a research hotspot. Ourcompany adopts special crafts to make LMW-HA. HA with differentmolecular weight can be customized. The minimum molecular weight is3000. Our HA 3000 has a good reputation in Japanese marketalready.