Citicoline (CDP-Choline)

 Chemical name: cytidine5''-diphosphocholine  

CAS No.: 987-78-0

EINECS No.: 213-580-7

Molecular Formula: C14H25N4O11P2

Formula Weight: 488.33

Citicoline(CDP-Choline):

Citicoline is the active principle of theciticoline sodium which indications are acute

traumatic braininjury and brain consciousness after the operation, treat centralnervous

system dysfunctionand unconsciousness caused by acute injury, paralysis agitans,tinnitus

and nervedeafness, and poisoning caused by sleeping pills.

In recent years,Citicoline (CDP-Choline) is widely used in replenishesing brain''senergy, clinical for treatment of ischemic stroke, cerebralarteriosclerosis, multi-infarct dementia, and Alzheimer’s disease,and children viral encephalitis, glaucoma.

In the USA market,Citicoline is widely used in energy shot, health food, brainnutritional supplements ect.

InEurope and Asia market, the citicoline sodium (active principle is citicoline) is injection ororal grade medicine.

FunctionClaims

² Citicoline (CDP-Choline)can Improve brain cell membranestructure of phospholipid synthesis ------ Enhancedintelligence

² Citicoline (CDP-Choline) Restoreelectrolyte balance, and promote the absorption of brain edema------- repair brain damage

² Citicoline (CDP-Choline)Regulate neurotransmitter synthesis and release, to keep it in asuitable concentration, stability, neurons in the middle of thetransmission ------anti-amnesic, anti-hypoxia

² Bioavailability:

² Safe ------ adverse reactions,no obvious side effects, safety, good.

3. Physiological Function

Citicoline is a nucleic acid thatis also known as CDP-choline. It is a form of choline that servesas the raw material for the production of phospholipids in thebrain. Brain cells have the ability to convert citicoline intophosphatidyl choline, the primary phospholipids component found incell membranes.

Citicoline is believed tostabilize the membranes and, when absorbed by the body, breaks downinto cytidine and choline. However, once citicoline reforms in thebody, it is converted to acetylcholine, a neurotransmitter, whichis involved in memory, thought, sexual function and other vitalfunctions. Numerous studies have indicated that when taken as asupplement, citicoline can lessen the symptoms of Alzheimer’sand

Parkinson’s disease, as well asalleviate mild cognitive impairment associated with ageing andstrokes.

citicoline can helps supply the nutrientswhich the human brain needs to stay alert and focused

The citicolinecan effectively reduce damage to cell membranes