DL-Tetrahydroberberine
DL-Tetrahydroberberine is racemic form that hydrided from naturalBerberine. It contains two optical isomers. Currently, severals ofdomestic and international research institutions worked togetherfor many years for finding a kind of antiarrhythmic drug that ishydrogenated berberine as the precursors.
A kind of antiarrhythmic drug derived from Canadine withproprietary intellectual property rights will be used for clinicalpurposes soon.
The products derived from the active ingredients of natural plantCoptis chinensis Franch, Phellodendron amurense Rupr, Corydatsyabhusuo W. T. Wang and Berberis julianae Schneid...
Trade Name: Canadine [ (R)-canadine (S)-Canadine ]
CAS No.: 522-97-4
Chemical Name: DL-Tetrahydroberberine DL-Canadine, (d,l)-Tetrahydroberberine (d, l)- Canadine
Molecular Formula: C20H21NO4
Molecular Weight: 339.39
Molecular Structure:
Specification:
Cannadine ≥ 90%-98%
Appearance light yellow-needle crystal
Melting Point 166-169° C
Loss on drying ≤ 1.0%
Arsenic ≤ 2ppm
Heavy metal ≤ 10ppm
Ignition Residual ≤ 0.5%
Microorganism ≤ 100 cfu/g
The date of 1H NMR
δ : 6.95 (1H, s)
6.91 (1H, d, J = 7.5 Hz) 6.80 (1H, d, J = 7.5 Hz)
6.64 (1H, s)
5.95 (2H, s)
3.86 (3H, s) 3.83 (3H, s)