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CAS NO.1446502-11-9Product Name EnasidenibSynonymsAG-221FormulaC19H17F6N7OMolecular Weight473.14Spec / Purity98%minSupply Capacity Details Enasidenib, aslo known as AG-221 and CC-90007, is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2). The mutations of IDH2 present in certain cancer cells result in a new ability of the enzyme to catalyze the NAPH-dependent reduction of a-ketoglutarate to R(-)-2-hydroxyglutarate (2HG). The production of 2HG is believed to contribute to the formation and progression of cancer . The inhibition of mutaEnasidenib CAS:1446502-11-9
2017-01-10 19:57 Views:171
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Company name:Shanghai Biopharmaleader co.,ltd
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Business contact:ChunleiZhang (Mr.)
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Area: Caribbean Region-Bermuda
Address:Building 11, NO. 3802 ShenGang Rd, Xinfei Corporation Home,
Zip:201611
Status:[Offline] [Send message] [Chat]
Business contact:ChunleiZhang (Mr.)
Telphone:
Mobile:
Fax:
Area: Caribbean Region-Bermuda
Address:Building 11, NO. 3802 ShenGang Rd, Xinfei Corporation Home,
Zip:201611